Kirtar's Wrath 
Sorcery
$0.22 #13826 0.42 25.1 years
Destroy all creatures. They can't be regenerated.
Threshold — If there are seven or more cards in your graveyard, instead destroy all creatures, then create two 1/1 white Spirit creature tokens with flying. Creatures destroyed this way can't be regenerated.
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Wrath of God91%
$3.27↑#687↑0.56↑33.2 years↑
"Destroy all creatures. They can't be regenerated."
Damnation91%
$17.37↑#391↑0.66↑19.7 years↓
"Destroy all creatures. They can't be regenerated."
Plague Wind88%
$2.61↑#6575↑0.56↑26.4 years↑
"Destroy all creatures you don't control. They can't be regenerated."
Toxic Stench86%
$0.19↓#28358↓0.08↓24.4 years
"If there are seven or more cards in your graveyard, instead destroy that creature. It can't be regenerated."
Winds of Rath86%
$0.33↑#1692↑0.53↑29.0 years↑
"Destroy all creatures that aren't enchanted. They can't be regenerated."
Consume the Meek86%
$0.16↓#19951↓0.20↓16.5 years↓
"Destroy each creature with mana value 3 or less. They can't be regenerated."
Shatterstorm84%
$0.30↑#17149↓0.64↑32.6 years↑
"Destroy all artifacts. They can't be regenerated."
Damn82%
$1.76↑#348↑0.435.5 years↓
"Destroy target creature. A creature destroyed this way can't be regenerated."
Terminate82%
$0.27↑#227↑0.20↓25.7 years
"Destroy target creature. It can't be regenerated."
Flesh to Dust82%
$0.04↓#25876↓0.00↓12.3 years↓
"Destroy target creature. It can't be regenerated."
Perish81%
$0.40↑#23105↓1.05↑29.0 years↑
"Destroy all green creatures. They can't be regenerated."
Mageta the Lion81%
$2.79↑#21519↓0.63↑26.4 years↑
"
, 
, Discard two cards: Destroy all creatures except for Mageta. Those creatures can't be regenerated."
, , Discard two cards: Destroy all creatures except for Mageta. Those creatures can't be regenerated."
Rout80%
$0.30↑#8157↑0.71↑26.0 years
"Destroy all creatures. They can't be regenerated."
Jokulhaups80%
$5.62↑#115372.59↑31.4 years↑
"Destroy all artifacts, creatures, and lands. They can't be regenerated."
Breaking Point80%
$0.27↑#19138↓0.25↓24.4 years
"Any player may have this card deal 6 damage to them. If no one does, destroy all creatures. Creatures destroyed this way can't be regenerated."
Planar Collapse80%
$0.41↑#18171↓0.87↑27.7 years↑
"At the beginning of your upkeep, if there are four or more creatures on the battlefield, sacrifice this enchantment and destroy all creatures. They can't be regenerated."
Catastrophe80%
$3.18↑#126352.00↑28.0 years↑
"Destroy all lands or all creatures. Creatures destroyed this way can't be regenerated."
March of Souls80%
$2.64↑#18676↓0.28↓25.7 years
"Destroy all creatures. They can't be regenerated. For each creature destroyed this way, its controller creates a 1/1 white Spirit creature token with flying."
Obliterate78%
$3.76↑#9603↑2.58↑26.0 years
"Destroy all artifacts, creatures, and lands. They can't be regenerated."
Retribution of the Meek78%
$7.82↑#127610.18↓29.7 years↑
"Destroy all creatures with power 4 or greater. They can't be regenerated."